Multiple unit effervescent dosage form

Details Multiple unit effervescent dosage form Multiple unit effervescent dosage form

A - Human Necessities

61

K

A61K 9/46 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 31/138 (2006.01) A61K 31/19 (2006.01) A61K 31/34 (2006.01) A61K 31/341 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/635 (2006.01) A61P 1/04 (2006.01) A61P 7/10 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2294744

The present invention is related to an effervescent pharmaceutical preparation comprising effervescent excipients and a plurality of individual units comprising a pharmaceutically active compound and optional excipients wherein the units (1) are provided with a floating generating system. The floating generating system comprises at least two coating layers, one of which is a gas generating layer (2) and the other layer is a barrier layer (3) enclosing the generated gas. Furthermore the invention is related to a process for the manufacture of the dosage forms, and their use in medicine.

La présente invention porte sur une préparation pharmaceutique effervescente comprenant des excipients effervescents et une pluralité d'unités individuelles comprenant un composé pharmaceutiquement actif et d'éventuels excipients. Les unités (1) comportent un système générant un flottement. Ce système générant un flottement comprend au moins deux couches, l'une d'elles étant une couche (2) générant un gaz et l'autre une couche barrière (3) renfermant le gaz généré. L'invention porte également sur un procédé de fabrication de formes galéniques et sur leur utilisation en médecine.

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