Multiple-unit sustained release tablets

Details Multiple-unit sustained release tablets Multiple-unit sustained release tablets

A - Human Necessities

61

K

A61K 9/26 (2006.01) A61K 9/20 (2006.01) A61K 9/52 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2328154

A multiple-unit sustained release tablet characterized by consisting of a granular part and a powdery part, each granule comprising a matrix composed of a water-insoluble polymer and the active ingredient. Another tablet characterized in that each granule is coated with a release-controlling film. These tablets show little change in elution speed caused by the compression in the tabletting step.

La présente invention concerne un comprimé à libération prolongée à unités multiples caractérisé en ce qu'il est constitué d'une partie granulaire et d'une partie en poudre. Chaque granule comprend une matrice se composant d'un polymère hydrosoluble et d'un principe actif. L'invention concerne également un autre comprimé caractérisé en ce que chaque granule est enrobé d'un film de régulation de la libération. La compression intervenant pour la confection de ces comprimés n'en modifie pratiquement pas la vitesse d'élution.

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