Multiple unit tablet compositions of benzimidazole compounds

Details Multiple unit tablet compositions of benzimidazole compounds Multiple unit tablet compositions of benzimidazole compounds

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 31/4439 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2667039

The present invention relates to multiple unit tablet compositions of benzimidazole compounds and process of preparation thereof. The compositions are useful against various gastrointestinal disorders. The multiple unit tablet composition comprises: a) tablet excipients, and b) multiple enteric coated core units containing a benzimidazole compound, wherein each core unit is covered with an enteric coating layer comprising a plasticizer in an amount of less than 15% by weight of the enteric coating layer polymer.

La présente invention porte sur des compositions de comprimés à multiples unités composés de benzimidazole et sur un procédé de préparation de celle-ci. Les compositions sont utiles contre divers troubles gastro-intestinaux. La composition de comprimés à multiples unités comprend : a) des excipients de comprimés, et b) de multiples unités de cAEur à enrobage entérique qui contiennent un composé de benzimidazole, chaque unité de cAEur étant enrobée d'une couche d'enrobage entérique contenant un plastifiant dans une quantité inférieure à 15 % en poids du polymère de couche d'enrobage entérique.

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