Multiple vaccination including serogroup c meningococcus

Details Multiple vaccination including serogroup c meningococcus Multiple vaccination including serogroup c meningococcus

A - Human Necessities

61

K

A61K 39/09 (2006.01) A61K 39/095 (2006.01) A61K 39/13 (2006.01) A61K 39/29 (2006.01) A61K 39/295 (2006.01)

Patent

CA 2621023

Various improvements to vaccines that include a serogroup C meningococcal conjugate antigen, including: (a) co-administration with acellular B.pertussis antigen; (b) co-administration with an inactivated poliovirus antigen; (c) supply in a kit together with a separate pneumococcal conjugate component, which may be in a liquid form; and (d) use in combination with a pneumococcal conjugate antigen but without an aluminium phosphate adjuvant. A kit may have: (a) a first immunogenic component that comprises an aqueous formulation of a conjugated capsular saccharide from Streptococcus pneumoniae; and (b) a second immunogenic component that comprises a conjugated capsular saccharide from Neisseria meningitidis serogroup C.

L'invention porte sur diverses améliorations apportées aux vaccins contenant un antigène méningogoccique conjugué du sérogroupe C. Ces améliorations comprennent: (a) la co-administration avec un antigène de B.pertussis, (b) la co-administration avec un antigène de poliovirus inactivé; (c) la présentation sous forme de trousse en combinaison avec un composant conjugué pneumococcique pouvant se présenter sous forme liquide; et (d) l'utilisation de ces vaccins en combinaison avec un antigène pneumococcique conjugué mais sans adjuvant de phosphate d'aluminium. La trousse décrite peut comprendre: (a) un premier composant immunogène comprenant une préparation aqueuse contenant un saccharide capsulaire conjugué de Streptococcus pneumoniae; et (b) un second composant immunogène comprenant un saccharide capsulaire conjugué du sérogroupe C de Neisseria meningitidis.

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