C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) C12N 5/071 (2010.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2474339
Methods and compositions are provided for screening candidate antiviral agents using cells containing subgenomic viral replication systems such as replicons and minigenomes. The methods involve the simultaneous assay of more than one subgenomic viral replication system. Compositions useful for theses methods are also provided.
L'invention concerne des procédés et des compositions de criblage d'agents antiviraux candidats au moyen de cellules contenant des systèmes de réplication virale subgénomiques tels que les unités de réplication et les minigénomes. Ces procédés impliquent l'analyse simultanée de plus d'un système de réplication virale subgénomique. L'invention concerne par ailleurs des compositions utilisées pour ces procédés.
Dyall Julie
Olivo Paul D.
Romano Charles P.
Roth Robert M.
Apath Llc
Osler Hoskin & Harcourt Llp
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