Multiplex vaccines

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/385 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2537900

The present invention provides antigen complexes comprising 15 or more, in some instances 15 to 100 or more, different antigens and/or compositions comprising the antigen complexes where the composition comprises 15 or more, in some instances 15 to 100 or more, different antigens. The invention also provides to methods of modulating immune responses through administration of the complexes to an individual and to methods of identifying immunodominant epitopes with use of the antigen complexes.

L'invention concerne des complexes d'antigènes comprenant au moins 15, parfois entre 15 et 100, voire davantage, antigènes différents et/ou compositions comprenant les complexes d'antigènes dans lesquels la composition comprend au moins 15, parfois entre 15 et 100, voire davantage, antigènes différents. L'invention concerne également des procédés permettant de moduler des réponses immunitaires par administration des complexes à un patients, ainsi que des procédés permettant d'identifier des épitopes immunodominants avec utilisation des complexes d'antigènes.

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