C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) A61K 31/7105 (2006.01) A61K 31/7115 (2006.01) A61K 31/712 (2006.01) A61K 31/713 (2006.01) C12N 15/00 (2006.01)
Patent
CA 2630932
Interfering RNA molecules are now designed and produced with specificity for multiple binding sequences present in distinct genetic contexts in one or more pre-selected target RNA molecules and are used to modulate expression of the target sequences. Such a multitargeting interfering RNA approach provides a powerful tool for gene regulation.
L'invention concerne des molécules d'ARN interférent conçues et produites de manière spécifique pour de multiples séquences de liaison présentes dans différents contextes génétiques dans une ou plusieurs molécules d'ARN cibles présélectionnées, et utilisées pour moduler l'expression des séquences cibles. Une telle approche de multiciblage par ARNs interférents permet d'obtenir un outil puissant de régulation génique.
Arndt Gregory Martin
Birkett Donald John
Passioura Toby
Poidinger Michael
Rivory Laurent Pierre
Johnson & Johnson Research Pty Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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