Multivalent aptamer therapeutics with improved...

Details Multivalent aptamer therapeutics with improved... Multivalent aptamer therapeutics with improved...

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2504633

Materials and methods are provided for producing aptamer therapeutics having improved pharmacokinetic and pharmacodymanic properties, as well as increased target valency. The aptamers produced by the methods of the invention are useful as therapeutics for treating disease.

L'invention concerne des substances et des procédés permettant de produire des agents thérapeutiques aptamères possédant des propriétés pharmacocinétiques et pharmacodynamiques améliorées, ainsi qu'une valence cible accrue. Les aptamères produits au moyen des procédés selon l'invention sont utiles comme agents thérapeutiques permettant de traiter des maladies.

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