Multivalent single chain antibodies

Details Multivalent single chain antibodies Multivalent single chain antibodies

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 16/30 (2006.01) C07K 16/42 (2006.01) C07K 16/46 (2006.01) C12N 15/13 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2117477

The present invention discloses multivalent single chain antibodies which have two or more biologically active antigen binding sites. The multivalent single chain antibodies are formed by using a peptide linker to covalently link two or more single chain antibodies, each single chain antibody having a variable light domain linked to a variable heavy chain domain by a peptide linker.

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