Multivalent t.d. polio vaccine against at least diphtheria,...

A - Human Necessities – 61 – K

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Details

A61K 39/295 (2006.01) A61K 39/05 (2006.01) A61K 39/08 (2006.01)

Patent

CA 2352617

The invention concerns a vaccine comprising: less than 1.2 mg per ml of aluminium salt; immunogenic antigens derived from at least the poliovirus, of Corynebacterium diphteriae and of Clostridium tetani; an amount of diphtheria toxin used as immunogenic antigen of Corynebacterium diphteriae between 4-16 Lf per ml. The invention also concerns the use thereof in primary vaccination and/or booster dose as well as a pharmaceutical kit comprising at least two injection doses of said vaccine.

La présente invention a pour objet un vaccin comprenant: moins de 1,2 mg par ml de sel d'aluminium; des antigènes immunogènes provenant au moins du poliovirus, de Corynebacterium diphteriae et de Clostridium tetani; et une quantité d'anatoxine diphtérique utilisée comme antigène immunogène de Corynebacterium diphteriae comprise entre 4-16 Lf par ml, son utilisation en primo-vaccination et/ou en vaccination de rappel et concerne également un Kit pharmaceutique comprenant au moins 2 doses injectables dudit vaccin.

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