Multivesicular liposomes having a biologically active...

Details Multivesicular liposomes having a biologically active... Multivesicular liposomes having a biologically active...

A - Human Necessities

61

K

167/163

A61K 9/127 (2006.01)

Patent

CA 1323568

Multivesicular Liposomes Having a Biologically Active Substance Encapsulated Therein In the Presence of a Hydrochloride Abstract of the Disclosure Disclosed are large multivesicular liposomes containing biologically active substances, the multivesicular liposomes having defined size distribution, adjustible average size, adjustible internal chamber size and number, and having substantially higher encapsulation efficiency and substantially slower leakage rate of the biologically active substance than in the previous art. The process comprises dissolving a lipid component in volatile organic solvents, adding an immiscible aqueous component containing a hydrochloride and one or more biologically active substances to be encapsulated, making a water-in-oil emulsion from the two components, immersing the emulsion into a second aqueous component, dividing the emulsion into small solvent spherules which contain even smaller aqueous chambers, and then evaporating the solvents to give an aqueous suspension of multivesicular liposomes encapsulating biologically active substances.

559596

Affiliated with

Also associated with

Rating

Multivesicular liposomes having a biologically active... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Multivesicular liposomes having a biologically active..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multivesicular liposomes having a biologically active... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1195489