A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/166, 71/47,
A61K 9/50 (2006.01) A01N 25/28 (2006.01) A61K 9/16 (2006.01) A61K 9/58 (2006.01) B01J 13/02 (2006.01)
Patent
CA 1336068
A single step method for preparation of multi-layer polymeric delivery systems. Any two or three different degradable or non-degradable polymers which are not soluble in each other at a particular concentration, as dictated by their phase diagram, can be used. The multi-layer microcapsules produced by the method are distinguished by extremely uniform dimensioned layers of polymer and actual incorporation of the substance to be delivered into the polymer layers. In the preferred embodiment of the method, two polymers are dissolved in a volatile organic solvent, the substance to be encapsulated is dispersed or dissolved in the polymer solution, the mixture is suspended in an aqueous solution and stirred, and the solvent is slowly evaporated, creating microspheres with an inner core formed by one polymer and an outer layer formed by the second polymer. In another embodiment one polymer may be formed within a layer of the other polymer by increasing the rate of evaporation of the volatile solvent.
565439
Langer Robert S.
Mathiowitz Edith
Massachusetts Institute Of Technology
Ridout & Maybee Llp
LandOfFree
Multiwall polymeric microcapsules does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multiwall polymeric microcapsules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multiwall polymeric microcapsules will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1208365