Multizymes and their use in making polyunsaturated fatty acids

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/00 (2006.01) C12N 9/02 (2006.01) C12N 15/62 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2679988

Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding multizymes (i.e., single polypeptides having at least two independent and separable enzymatic activities) along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these multizymes in plants and oleaginous yeast are disclosed.

L'invention concerne des fragments d'acides nucléiques isolés et des constructions de recombinaison comprenant lesdits fragments codant pour les multienzymes (à savoir, des polypeptides uniques présentant au moins deux activités enzymatiques indépendantes et séparables) ainsi qu'un procédé de production d'acides gras polyinsaturés à chaîne longue (PUFA) faisant intervenir ces multienzymes dans des plantes et des levures oléagineuses.

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