Muramyl peptides and processes for their manufacture

C - Chemistry – Metallurgy – 07 – K

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530/9, 167/103.8

C07K 9/00 (2006.01)

Patent

CA 1243305

Abstract The compounds of the formula I (I) Image in which each of R1, R4 and R6, independently of the others, represents hydrogen or lower alkanoyl, R2 represents C1-4-alkyl, hydroxymethyl or phenyl, R3 represents hydrogen or methyl, R5 represents hydrogen or C1-3-alkyl, R7 represents C1-3-alkyl that is unsub- stituted or substituted by hydroxy, mercapto or methylthio, R8 represents hydrogen or lower alkyl, X represents oxygen or the group NH, Y represents C1-4-alkylidene, and each of R9 and R10, independently of the other, represents C11-17-alkyl or C11-17-alkenyl, and their salts, have an immunostimulating activity.

433038

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