Muramyldipeptide derivatives

Details Muramyldipeptide derivatives Muramyldipeptide derivatives

C - Chemistry, Metallurgy

07

K

530/9

C07K 9/00 (2006.01) B32B 5/24 (2006.01) D06N 3/00 (2006.01)

Patent

CA 1249400

ABSTRACT OF THE DISCLOSURE Muramyldipeptide derivatives represented by the formula: Image wherein Ala represents alanine; Acyl represents an acyl group; R1 and R2 each represents a hydrogen atom or, when taken together, may form an alkylidene group; R3 represents a hydrogen atom, an acyl group or an alkyl group; and R4 represents a hydrogen atom or an alkyl group. These compounds have excellent immunoadjuvant activity, prophyl- actic and therapeutic effects against microbial infections, and antitumor activity.

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