Muramyldipeptide derivatives and process for the preparation...

Details Muramyldipeptide derivatives and process for the preparation... Muramyldipeptide derivatives and process for the preparation...

C - Chemistry, Metallurgy

07

K

530/5.06

C07K 9/00 (2006.01)

Patent

CA 1105005

D-1-17921C/77 ABSTRACT OF THE DISCLOSURE Muramyldipeptide derivatives of the formula: Image wherein Y represents a mycoloyl group or a synthetic higher acyl group having total carbon number of C30-C90 and having at least a branched chain of long alkyl group on the .alpha.-position thereof, Q represents an -L-alanyl-D-isoglutamine group, a -glycyl-D-isoglutamine group or an -L-seryl-D-isoglutamine group; salts of such derivatives; the method for preparing such derivatives and their salts; the derivatives and their salts having potent immunoadjuvant activities and antitumor activity and being applicable as the agent for the immunotherapy of cancer for humans and animals.

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