Muramylpeptide active ester derivatives

Details Muramylpeptide active ester derivatives Muramylpeptide active ester derivatives

C - Chemistry, Metallurgy

07

K

530/9

C07K 9/00 (2006.01) A61K 37/02 (1985.01)

Patent

CA 1272850

ABSTRACT OF THE DISCLOSURE Muramylpeptide active ester derivatives represented by the formula: Image wherein R1 represents a hydrogen atom or a fatty acid residue having from 2 to 10 carbon atoms; -COR2 repre- sents an active ester group; R3 represents a fatty acid residue having from 1 to 10 carbon atoms; X represents an alanine, N-methylalanine or valine residue; "Acyl" represents a fatty acid residue having from 2 to 6 carbon atoms; and n represents an integer of from 1 to 6. These compounds are applicable as haptens for the immunotherapy and exhibit antitumor activity.

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