Murd protein and gene of pseudomonas aeruginosa

Details Murd protein and gene of pseudomonas aeruginosa Murd protein and gene of pseudomonas aeruginosa

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/02 (2006.01) A61K 39/108 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 9/00 (2006.01) C12N 15/00 (2006.01) C12N 15/20 (2006.01) C12P 21/04 (2006.01) C12P 21/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2333667

This invention provides isolated polynucleotides that encode the MurD protein of Pseudomonas aeruginosa. Purified and isolated MurD recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurD proteins are described. Assays for the identification of modulators of the of expression of murD and inhibitors of the activity of MurD, are also provided.

L'invention concerne des polynucléotides isolés, codant la protéine MurD de Pseudomonas aeruginosa. Elle concerne également des protéines recombinées MurD, purifiées et isolées, des séquences d'acides nucléiques codant les protéines MurD fonctionnement actives, ainsi que des dosages destinés à l'identification de modulateurs de l'expression de murD et d'inhibiteurs de l'activité de MurD.

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