Murd protein and gene of staphylococcus aureus

Details Murd protein and gene of staphylococcus aureus Murd protein and gene of staphylococcus aureus

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) C12N 1/20 (2006.01) C12N 9/00 (2006.01) C12N 9/10 (2006.01) C12N 15/00 (2006.01) C12N 15/54 (2006.01) C12P 21/06 (2006.01)

Patent

CA 2308620

This invention provides the murD gene of Staphylococcus aureus. Purified and isolated MurD recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurD proteins are described. Assays for the identification of modulators of the expression of murD and inhibitors of the activity of MurD, are also provided.

L'invention concerne le gène murD du staphylocoque doré. L'invention traite aussi de protéines de recombinaison MurD isolées et purifiées, ainsi que des séquences d'acide nucléique qui codent des protéines MurD actives du point de vue fonctionnel. L'invention a aussi pour objet des dosages permettant d'identifier les modulateurs de l'expression du gène murD et des inhibiteurs de l'activité du MurD.

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