Murd protein and gene of streptococcus pyogenes

Details Murd protein and gene of streptococcus pyogenes Murd protein and gene of streptococcus pyogenes

C - Chemistry, Metallurgy

12

N

C12N 1/00 (2006.01) C12N 5/10 (2006.01) C12N 9/00 (2006.01) C12N 15/52 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2309005

This invention provides the murD gene of Streptococcus pyogenes. Purified and isolated MurD recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurD proteins are described. Assays for the identification of modulators of the expression of murD and inhibitors of the activity of MurD, are also provided.

L'invention concerne le gène murD de Streptococcus pyogenes, ainsi que des protéines murD recombinantes isolées et purifiées. On décrit également des séquences d'acide nucléique codant des protéines murD fonctionnellement actives. On décrit enfin des dosages permettant d'identifier des modulateurs de l'expression de murD et des inhibiteurs de l'activité de murD.

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