Murine ortholog of the human disrupted-in-schizophrenia 1 gene

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2483201

The present invention features Disc1 polypeptides, Disc1 nucleic acids, and recombinant Disc1 altered mice. The Disc1 amino acid sequence of SEQ ID NO: 1 and the nucleic acid sequence of SEQ ID NO: 2 provide the mouse ortholog to the human DISC1 amino acid sequence and nucleic acid sequence.

La présente invention concerne des polypeptides de Disc-1, des acides nucléiques de Disc-1, ainsi que des souris transgéniques contenant le gène recombiné Disc-1. La séquence d'acides aminés de Disc-1 de SEQ ID NO :1 et la séquence d'acides nucléiques de SEQ ID NO :2 permettent d'obtenir l'orthologue murin des séquences humaines d'acides nucléiques et d'acides aminés de Disc-1.

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