Muscarine antagonists

Details Muscarine antagonists Muscarine antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2200468

Compounds, 1,3-dihydro-1-{1-[piperidin-4-yl]piperidin-4-yl}-2H-benzimidazol-2- ones and 1,3-dihydro-1-{4-amino-1-cyclohexyl}-2H-benzimidazol-2-ones and derivatives thereof, their preparation, method of use and pharmaceutical compositions are described. These compounds are endowed with antimuscarinic activity and are useful in the treatment and/or prevention of myopia (commonly known as nearsightedness).

Composés, 1,3-dihydro-1-{1-[pipéridine-4-yl]pipéridine-4-yl}-2H-benzimidazole-2-ones et 1,3 dihydro-1-{4-amino-1-cyclohexyl}-2H-benzimidazole-2-ones et dérivés desdites substances, leur préparation, procédé d'utilisation et compositions pharmaceutiques. Lesdits composés possèdent une activité antimuscarinique et sont utiles dans le traitement et/ou la prévention de la myopie.

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