Muscarinic agonists

Details Muscarinic agonists Muscarinic agonists

C - Chemistry, Metallurgy

07

D

C07D 239/06 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) C07D 211/72 (2006.01) C07D 211/78 (2006.01) C07D 405/04 (2006.01) C07D 411/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2113424

Substituted 1,4,5,6-tetrahydropyrimidine compositions, substituted 1,2,3,6-tetrahydropyrimidine compositions and substituted 3,4,5,6-tetrahydropyridine compositions of the formulae (see formulae I, II, III) where A, R and Z, are various functional groups, are disclosed. They are useful for stimulating muscarinic receptors including, for example, treating the symptoms of cognitive disorders, especially impaired memory, which are associated with decreased acetylcholine synthesis and cholinergic cell degeneration.

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