Muscarinic m1 receptor agonists for pain management

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/538 (2006.01) A61K 31/454 (2006.01) A61P 25/02 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2520125

Disclosed herein are compounds and methods for treating chronic neuropathic pain. It has been discovered that compounds that selectively interact with a muscarinic receptor subtype are effective in treating neuropathic pain. Specifically, compounds that selectively interact with the M1 muscarinic receptor subtype may be used.

L'invention concerne des composés et de méthodes de traitement de la douleur neuropathique chronique. On a découvert que des composés qui interagissent sélectivement avec un sous-type de récepteur muscarinique permettant de combattre efficacement la douleur neuropathique. Spécifiquement, il est possible d'utiliser des composés qui interagissent sélectivement avec le sous-type M1 de récepteur muscarinique.

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