Mutant bank

Details Mutant bank Mutant bank

C - Chemistry, Metallurgy

12

N

C12N 1/16 (2006.01) A61K 48/00 (2006.01) C07K 14/38 (2006.01) C12N 15/80 (2006.01) C12N 15/81 (2006.01)

Patent

CA 2403317

The invention relates to a mutant bank of diploid micro-organisms which consists of a population of mutant cells in which at least one cell has a random mutation which disrupts the activity of at least one gene, wherein the micro-organism is inducible into haploid form. The invention further relates to a method of using the mutant bank to identify the genes which contribute to a chosen phenotype.

L'invention concerne une banque de mutants de micro-organismes diploïdes, comprenant une population de cellules mutantes dans laquelle au moins une cellule possède une mutation aléatoire qui interrompt l'activité d'au moins un gène, le micro-organisme prenant ainsi une forme haploïde. L'invention concerne également un procédé d'utilisation de cette banque de mutants pour l'identification de gènes correspondant à un phénotype donné.

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