Mutant bcl-2 proteins and uses thereof

Details Mutant bcl-2 proteins and uses thereof Mutant bcl-2 proteins and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2427658

Mutant peptides derived from wild-type human Bcl-2 are disclosed. Assays to identify substances which block the ability of Bcl-2 to inhibit apoptosis also are disclosed.

L'invention concerne des peptides mutants dérivés de la protéine Bcl-2 humaine de type sauvage, ainsi que des dosages servant à identifier des substances qui bloquent la capacité de la protéine Bcl-2 à inhiber l'apoptose.

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