Mutant microorganisms having high ability to produce...

Details Mutant microorganisms having high ability to produce... Mutant microorganisms having high ability to produce...

C - Chemistry, Metallurgy

12

N

C12N 1/21 (2006.01) C12N 1/19 (2006.01) C12N 15/00 (2006.01) C12N 15/54 (2006.01) C12N 15/63 (2006.01) C12P 13/00 (2006.01)

Patent

CA 2700510

The present invention relates to mutant microorganisms having high ability to produce putrescine in which genes involved in the putrescine degradation or utilization pathway of microorganisms having a putrescine-producing metabolic pathway are inactivated or deleted; and a method for producing putrescine in high yield by culturing the mutant microorganisms under anaerobic conditions. The mutant microorganisms having high ability to produce putrescine are useful for producing a high yield of putrescine which is used in a wide range of industrial applications.

L'invention concerne un micro-organisme mutant présentant une aptitude élevée à produire de la putrescine, dans lequel les gènes associés à la décomposition ou à la voie d'utilisation de la putrescine sont affaiblis ou supprimés, ledit micro-organisme présentant une voie métabolique de production de putrescine. L'invention concerne également un procédé de préparation de putrescine à haut rendement par culture dudit micro-organisme mutant dans des conditions anaérobies. Le micro-organisme mutant présentant une aptitude élevée à produire de la putrescine selon l'invention est utile pour produire de la putrescine à haut rendement et présente un vaste potentiel d'applications industrielles.

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