Mutant proteins having lower allergenic response in humans...

Details Mutant proteins having lower allergenic response in humans... Mutant proteins having lower allergenic response in humans...

C - Chemistry, Metallurgy

12

N

C12N 15/57 (2006.01) C12N 1/21 (2006.01) C12N 9/54 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2327311

The present invention relates to a novel improved protein mutant which produces low allergenic response in humans compared to the parent of that mutant. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein.

La présente invention concerne un nouveau mutant protéique amélioré produisant une faible réponse allergène chez l'homme par rapport à une protéine précurseur de ce mutant. La présente invention concerne plus particulièrement la neutralisation ou la réduction de la capacité des cellules T à reconnaître les épitopes, ce qui permet de prévenir la sensibilisation d'un individu à ladite protéine.

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