Mutant respiratory syncytial virus (rsv) vaccines containing...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/01 (2006.01) A61K 39/155 (2006.01) C07K 14/135 (2006.01) C12N 7/08 (2006.01) C12N 15/45 (2006.01) C12N 15/62 (2006.01) C12N 15/86 (2006.01) C12N 15/87 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2094464

This invention provides cold adapted mutant RSV, specifically, mutant RSV of subgroup A and B. Nucleic acid molecules encoding the mutant RSV of this invention, and immunogenic polypeptides of these mutant RSV also are provided by this invention. Pharmaceutical compositions containing any of the above compositions are provided herein. These are especially useful as vaccines. Further provided by this invention are methods of vaccinating a subject against RSV infection using the pharmaceutical compositions described herein.

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