Mutant saccharomyces cerevisiae strain utilizing xylose for...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/19 (2006.01) C12P 7/06 (2006.01)

Patent

CA 2566189

The present invention relates to a new xylose utilizing Saccharomyces cerevisiae strain being able to utilize xylose for ethanol production which strain is up-regulated with regard to the genes for xylose reductase (XR) and xylulose dehydrogenase (XDH) as well as xululokinase (XK) and over-expressing the non-oxidative pentose phosphate pathway (PPP) and comprising a deletion of the gene GRE3 deletion, as well as the strain has been adapted to xylose feeding.

L'invention concerne un nouveau xylose utilisant une souche deSaccharomyces cerevisiae pour produire de l'éthanol. Cette souche est régulée positivement par rapport aux gènes de la xylose réductase (XR), de la xylulose déhydrogénase (XDH) et de la xylulokinase (XK). Ladite souche permet de surexprimer le chemin pentose phosphate non oxydatif (PPP), comprend une délétion du gène GRE3, et a été conçue pour fournir un xylose.

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