C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/21 (2006.01) A61K 35/74 (2006.01) A61K 39/02 (2006.01) A61P 31/04 (2006.01) A61P 37/04 (2006.01) C12N 1/20 (2006.01) C12N 15/00 (2006.01) C12N 15/31 (2006.01)
Patent
CA 2760098
The present invention relates to a mutant Francisella tularensis strain comprising an inactivated clpB gene and compositions comprising such mutant. Methods of producing the mutant are also described. The present invention also encompasses a method of conferring immunity against F. tularensis in a host, comprising administering the described mutant F. tularensis strain.
La présente invention porte sur une souche mutante de Francisella tularensis comprenant un gène clpB inactivé et sur des compositions comprenant un tel mutant. L'invention porte également sur des procédés de production du mutant. La présente invention porte également sur un procédé consistant à conférer une immunité contre F. tularensis chez un hôte, comprenant l'administration de la souche mutante de F. tularensis décrite.
Conlan Joseph Wayne
Sjostedt Anders
National Research Council Of Canada
Patenaude Sonia
LandOfFree
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