Mutants of urinary plasminogen activator, their production...

Details Mutants of urinary plasminogen activator, their production... Mutants of urinary plasminogen activator, their production...

C - Chemistry, Metallurgy

12

N

195/39.1, 195/1.

C12N 15/63 (2006.01) C12N 1/00 (2006.01) C12N 9/68 (2006.01) C12N 9/72 (2006.01) C12N 15/58 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2012346

BEHRINGWERKE AKTIENGESELLSCHAFT 83/B 009 - Ma 731 Dr. Lp/rd Abstract Mutants of Urinary Plasminogen Activator, Their Pro- duction and Use Mutants of urinary plasminogen activator are described having alone or in combination a change of the glyco- sylation pattern, truncation of the N-terminus, and modification of the cleavage site. These polypeptides are produced by expression of mutated genes created by site directed mutagenesis.

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