Mutated form of the .beta.-amyloid precursor protein gene

Details Mutated form of the .beta.-amyloid precursor protein gene Mutated form of the .beta.-amyloid precursor protein gene

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07H 21/04 (2006.01) C07K 7/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2108548

ABSTRACT MUTATED FORM OF THE .beta.-AMYLOID PRECURSOR PROTEIN GENE The invention relates to a polypeptide containing a sequence of contiguous amino acids of the polypeptide sequence coded by exon 17 of the cDNA of the APP 770 gene, with said sequence of contiguous amino acids being such that: - it has from 5 to the total number of amino acids coded by said exon 17, - and it contains the amino acid corresponding to codon 692 in the cDNA of the APP 770 gene and which is alanine substituted for glycine. (no figure).

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