A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 38/45 (2006.01) C07K 14/71 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2117073
Abstract The present invention relates to mutated growth factor receptors which are suited as a drug. The mutated growth factor receptors as especially advantageous for the treatment of cancer diseases, in particular of those types of cancer, in which the overactivity of growth factor receptors plays a role in the development of cancer and other diseases based on the overactivity of the receptors. Mutants of the EGF receptor are disclosed as an especially effective drug for the treatment of cancer, in which the tyrosine kinase activity of the wild-type receptor was eliminated by a point mutation or deletion in the tyrosine kinase domain.
Redemann Norbert
Ullrich Axel
Max Planck Gesellschaft Zur Forderung Der Wissenschaften E.v.
Riches Mckenzie & Herbert Llp
LandOfFree
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