Mutated hiv nef for modulating immunity

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/21 (2006.01) A61K 38/16 (2006.01) A61P 31/18 (2006.01) A61P 37/02 (2006.01) C07K 16/10 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2577183

The present invention relates to the use of a mutation of at least one amino acid in the immunosuppressive domain of a HIV or SIV accessory protein, for modulating the immunosuppressive property of said protein.

L'invention concerne l'utilisation d'une mutation d'au moins un acide aminé du domaine immunodépresseur d'une protéine accessoire du VIH ou du VIS en vue de moduler la propriété d'immunodépression de cette protéine.

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