Mutated hiv tat

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/48 (2006.01) A61K 31/7088 (2006.01) A61K 38/16 (2006.01) A61K 39/21 (2006.01) A61K 39/39 (2006.01) A61K 48/00 (2006.01) A61P 31/18 (2006.01) C07K 14/16 (2006.01) C12N 15/49 (2006.01) C12N 15/85 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2469487

The present invention provides a Tat protein wherein all the cysteine residues of the cysteine-rich domain have been replaced with another amino acid, preferably with serine, nucleic acids encoding it, and methods of using it to elicit a humoral and cellular immune responses in a mammal. The Tat protein of the invention is therefore useful, inter alia, for prophylactic and/or therapeutic anti-HIV use as well as raising anti-native Tat antibodies in mammmals.

La présente invention concerne une protéine Tat dans laquelle tous les résidus de cystéine du domaine riche en cystéine ont été remplacés par un autre acide aminé, de préférence par la sérine; des acides nucléiques codant cette protéine et des méthodes d'utilisation de cette dernière pour éliciter des immuno-réponses humorale et cellulaire chez un animal. La protéine Tat selon la présente invention est par conséquent utile, entre autres, pour l'utilisation prophylactique et/ou thérapeutique contre le VIH ainsi que pour produire des anticorps Tat anti-natifs chez les mammifères.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Mutated hiv tat does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mutated hiv tat, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mutated hiv tat will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1761165

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.