Mutated netrin 4, fragments thereof and uses thereof as drugs

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/475 (2006.01) A61K 38/18 (2006.01)

Patent

CA 2675754

The present invention relates to a protein comprising or consisting of one of the following sequences: the sequence SEQ ID NO:2 or SEQ ID NO:4, or a fragment of said sequence represented by one of the sequences SEQ ID NO:2q, q varying from 3 to 36, or the sequence SEQ ID NO :185 to SEQ ID NO :209. It also relates to a nucleotide sequence coding for said protein.

L'invention concerne une protéine comprenant l'une des séquences suivantes, ou composée de l'une des séquences suivantes: *la séquence SEQ ID NO:2 ou SEQ ID NO:4, ou *un fragment de ladite séquence représenté par l'une des séquences SEQ ID NO:2q, q variant de 3 à 36, ou *l'une des séquences SEQ ID NO :185 à SEQ ID NO :209. L'invention se rapporte également à une séquence nucléotidique codant pour ladite protéine.

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