Mutated parvovirus structural proteins as vaccines

Details Mutated parvovirus structural proteins as vaccines Mutated parvovirus structural proteins as vaccines

G - Physics

01

N

G01N 33/53 (2006.01) A61K 39/00 (2006.01) A61K 39/295 (2006.01) C07K 14/015 (2006.01) C12N 15/864 (2006.01)

Patent

CA 2687728

The present invention is related to a method for identifying a parvovirus mutated structural protein capable of specifically binding to a binder for an antigen, a parvovirus mutated structural protein which comprises at least one B-cell epitope heterologous to the parvovirus, a multimeric structure comprising the protein, a nucleic acid encoding the protein, a virus or cell comprising the protein, a method of preparing the protein, a medicament comprising the protein, nucleic acid or multimeric structure and its use.

La présente invention porte sur un procédé d'identification d'une protéine structurale mutée de parvovirus capable de se lier spécifiquement à un liant pour un antigène, sur une protéine structurale mutée de parvovirus qui comporte au moins un épitope de lymphocyte B hétérologue au parvovirus, sur une structure multimère comportant la protéine, sur un acide nucléique codant pour la protéine, sur un virus ou une cellule comportant la protéine, sur un procédé de préparation de la protéine, sur un médicament comportant la protéine, l'acide nucléique ou la structure multimère et sur son utilisation.

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