Mutation associated with lacunar strokes

Details Mutation associated with lacunar strokes Mutation associated with lacunar strokes

C - Chemistry, Metallurgy

12

N

C12N 9/16 (2006.01)

Patent

CA 2597127

The present invention relates to a method of identifying a subject predisposed to lacunar stroke. The method includes the step of identifying in the subject the presence of a thymine to cytosine mutation at position -107 in both alleles of the paraoxonase 1 locus.

L'invention concerne une méthode d'identification d'un patient présentant une prédisposition à un accident vasculaire cérébral lacunaire. Cette méthode comprend l'étape consistant à identifier, chez le patient, la présence d'une mutation de thymine en cytosine, à la position 107, dans les deux allèles du locus de paraoxanase 1.

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