Mutation of hrv2 2a

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/41 (2006.01) A61K 38/55 (2006.01) C07K 14/095 (2006.01) C07K 14/81 (2006.01) C12N 9/50 (2006.01) C12N 9/99 (2006.01) C12N 15/57 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2072105

- 35 - Abstract The present invention relates to oligonucleotides which code for a modified active centre of HRV2 2A, the modifications affecting, preferably inhibiting, the "cis"-activity of the proteinase.

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