Mutation of the parkin gene, compositions, methods and uses

Details Mutation of the parkin gene, compositions, methods and uses Mutation of the parkin gene, compositions, methods and uses

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 25/16 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2351567

The invention concerns nucleic acids coding for mutated or truncated forms of the human parkin gene, or forms comprising multiplication of exons, and the corresponding proteins and antibodies. The invention also concerns methods and kits for identifying mutations of the parkin gene, and for studying compounds for therapeutic purposes.

La présente invention concerne des acides nucléiques codant pour des formes de la parkine humaine mutées, tronquées ou comportant des multiplications d'exons, et les protéines et anticorps correspondants. Elle concerne aussi des méthodes et kits pour l'identification de mutations du gène de la parkine, ainsi que pour l'étude de composés à visée thérapeutique.

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