Mutation scanning array, and methods of use thereof

Details Mutation scanning array, and methods of use thereof Mutation scanning array, and methods of use thereof

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2357601

The present method is directed to using a mutation scanning array to identify mismatches or polymorphisms in multiple genes or the same gene in multiple individuals. The array can be a chip or a microsphere. Preferably, the array has elements containing immobilized oligonucleotides that collectively span at least 10 different whole genes.

Cette invention a trait à l'utilisation d'un réseau de balayage de mutation permettant d'identifier des mésappariements ou des polymorphismes dans plusieurs gènes ou dans le même gène chez plusieurs individus. Ce réseau, qui peut être une microplaquette ou une microsphère, comporte, de préférence, des éléments contenant des oligonucléotides immobilisés qui, collectivement, couvrent au moins 10 gènes différents.

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