Mutations affecting plasmid copy number

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) C12N 15/69 (2006.01) C12N 15/70 (2006.01) C12P 21/02 (2006.01) C12P 21/06 (2006.01) C12P 23/00 (2006.01)

Patent

CA 2509702

Mutations in chromosomal genes have been identified that affect plasmid copy number in plasmids that are anti-sense RNA regulated such as the pMB1-derived and p15A-derived plasmids.

Selon l'invention, on a identifié des mutations dans des gènes chromosomiques qui affectent le nombre de copies de plasmides dans des plasmides régulés par l'ARN antisens, tels que les plasmides dérivés de pMB1 et de p15A.

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