Mutations in ion channels

Details Mutations in ion channels Mutations in ion channels

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A01K 67/02 (2006.01) A01K 67/027 (2006.01) A61K 31/711 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 3/10 (2006.01) A61P 3/12 (2006.01) A61P 9/06 (2006.01) A61P 21/04 (2006.01) A61P 25/02 (2006.01) A61P 25/06 (2006.01) A61P 25/08 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 29/02 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C07K 14/

Patent

CA 2454073

A method of identifying a subject predisposed to a disorder associated with ion channel dysfunction, comprising ascertaining whether at least one of the genes encoding ion channel subunits in said subject has undergone a mutation event such that a cDNA derived from said subject has the sequence set forth in one of SEQ ID NOS: 1-134.

L'invention concerne un procédé d'identification d'un sujet présentant une prédisposition à un trouble associé à un dysfonctionnement de canaux ioniques, consistant à déterminer si au moins un des gènes codant des sous-unités de canaux ioniques dudit sujet, a subi un événement de mutation, tel qu'un ADNc provenant dudit sujet présentant la séquence indiquée dans l'une des séquences SEQ ID NOS: 1-134.

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