Muteins of human erythropoietin, the preparation thereof and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/505 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2021528

The invention relates to muteins of human erythropoietin (EPO) in the carbonyl terminal region which are prepared by means of recombinant DNA techniques. Theses mutants have advantageous properties in comparison with human wild-type EPO.

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