C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2536491
The present invention relates to novel muteins derived from tear lipocalin or a homologue thereof. In particular, the invention relates to a mutein of human tear lipocalin. The invention also refers to a corresponding nucleic acid molecule encoding such a mutein and to a method for its generation. The invention further refers to a method for producing such a mutein. Finally, the invention is directed to a pharmaceutical composition comprising such a lipocalin mutein as well as to various use of the mutein.
L'invention concerne de nouvelles mutéines dérivées de lipocaline lacrymale ou un homologue de celles-ci. En particulier, l'invention concerne une mutéine de lipocaline du fluide lacrymal humain. L'invention concerne également une molécule d'acide nucléique correspondante codant pour une telle mutéine, et un procédé de génération de celle-ci. L'invention concerne, par ailleurs, un procédé de production d'une telle mutéine. Enfin, l'invention concerne une composition pharmaceutique comprenant une telle mutéine de lipocaline, ainsi que diverses utilisations de la mutéine.
Schlehuber Steffen
Skerra Arne
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Pieris Proteolab Ag
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