Mycobacterial diagnostics

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/31 (2006.01) A61K 39/04 (2006.01) C07H 21/00 (2006.01) C07K 1/00 (2006.01) C07K 14/35 (2006.01) C07K 16/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2498650

The present invention provides nucleic acid molecules unique to M. paratuberculosis. The invention also provides the polypeptides encoded by the M. paratuberculosis- specific nucleic acid molecules of the invention, and antibodies having specific binding affinity for the polypeptides encoded by the paratuberculosis- specific nucleic acid molecules. The invention further provides for methods of detecting M. paratuberculosis in a sample using nucleic acid molecules, polypeptides, and antibodies of the invention. The invention additionally provides methods of preventing a M. paratuberculosis infection in an animal.

La présente invention a trait à des molécules d'acide nucléique spécifiques de <I>M.</I> paratuberculosis. L'invention a également trait à des polypeptides codés par les molécules d'acide nucléique de l'invention spécifiques de M.paratuberculosis., et des anticorps présentant une affinité de liaison spécifique pour les polypeptides codés par les molécules d'acide nucléique spécifiques de <I>M.</I> paratuberculosis L'invention a trait en outre à des procédés de détection de <I>M.</I> paratuberculosis dans un échantillon utilisant des molécules d'acide nucléique, des polypeptides, et des anticorps de l'invention. L'invention a également trait à des procédés de prévention d'une infection de <I>M.</I> paratuberculosis chez un animal.

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