Mycobacterium strain with modified erp gene and vaccine...

Details Mycobacterium strain with modified erp gene and vaccine... Mycobacterium strain with modified erp gene and vaccine...

C - Chemistry, Metallurgy

07

K

C07K 14/35 (2006.01) A61K 48/00 (2006.01) C12N 1/21 (2006.01) C12N 1/36 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) G01N 33/53 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2298063

The invention concerns Mycobacterium strains whereof the erp gene is modified and a vaccine composition containing same. The modification of the erp gene decreases the virulence and the persistence of the Mycobacterium strains.

L'invention concerne des souches de Mycobacterium dont le gène erp est modifié ainsi que la composition vaccinale la contenant. La modification du gène erp diminue la virulence et la persistance des souches de Mycobacterium.

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