C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/04 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) C07K 14/35 (2006.01) C07K 19/00 (2006.01) C12N 1/19 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01) G01N 33/60 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2290774
Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
La présente invention concerne des composés et des procédés permettant d'induire une immunité protectrice contre la tuberculose. Les composés comprennent des polypeptides qui contiennent au moins une partie immunogène d'une ou plusieurs protéines M. tuberculosis et des molécules d'ADN codant lesdits polypeptides. Ces composés peuvent être formulés dans des vaccins et/ou des compositions phamaceutiques pour immunisation contre une infection M. tuberculosis ou peuvent être utilisés pour le diagnostic de la tuberculose.
Alderson Mark R.
Campos-Neto Antonio
Dillon Davin C.
Skeiky Yasir A. W.
Corixa Corporation
Gowling Lafleur Henderson Llp
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