Mycoplasma polypeptides

Details Mycoplasma polypeptides Mycoplasma polypeptides

C - Chemistry, Metallurgy

07

K

C07K 16/12 (2006.01) A61K 39/02 (2006.01) A61K 39/395 (2006.01) A61K 39/40 (2006.01) C07K 14/30 (2006.01) C12N 3/00 (2006.01) C12Q 1/37 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2481042

The invention provides methods and materials related to mycoplasma. For example, the invention provides mycoplasma polypeptides having the ability to increase calcium release from cells (e.g., porcine ciliated tracheal cells) as well as antibodies that bind to such mycoplasma polypeptides. In addition, the invention provides methods for identifying inhibitors of mycoplasma-induced calcium release from porcine ciliated tracheal cells.

L'invention concerne des procédés et des produits se rapportant au mycoplasme. Par exemple, l'invention concerne des polypeptides de mycoplasme capables d'accroître la mise en liberté du calcium à partir des cellules (par exemple, cellules trachéales cillées porcines), ainsi que des anticorps se liant à de tels polypeptides de mycoplasme. En outre, l'invention concerne des procédés permettant l'identification d'inhibiteurs de libération du calcium induite par le mycoplasme, à partir de cellules trachéales cilliées porcines.

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